Immune senescence and vaccines to prevent herpes zoster in older persons. Curr Opin Immunol . 2012;24(4):494-500. Chlibek R, Smetana J, Pauksens K, et al. Safety and immunogenicity of three different formulations of an adjuvanted varicella-zoster virus subunit candidate vaccine in older adults: a phase II, randomized, controlled study.

compared with non-adjuvanted vaccines.6 • SHINGRIX, a non-live vaccine, is the only shingles vaccine available formulated with an adjuvant. • SHINGRIX was designed as a two-dose vaccine. The second dose should be administered two to six months after the first dose.4 SHINGRIX Important Safety Information